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High-altitude hypoxia and echocardiographic indices of pulmonary hypertension in male and female chickens at adulthood
(Circulation Journal, 2014-06)
Background: By combining the chick embryo model with incubation at high altitude (HA), the effects of chronic hypoxia on fetal growth, fetal cardiac and aortic wall remodeling and systemic arterial blood pressure at adulthood ...
Exaggerated exercise-induced pulmonary hypertension causes lung water accumulation and right ventricular dysfunction in patients with chronic mountain sickness
(High Altitude Medicine & Biology, 2010-08-08)
Adrenocortical suppression in highland chick embryos is restored during incubation at sea level
(High Altitude Medicine & Biology, 2011)
Abstract.
By combining the chick embryo model with incubation at high altitude, this study tested the hypothesis that
development at high altitude is related to a fetal origin of adrenocortical but not adrenomedullary ...
Response to letters regarding article, "Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia"
(Circulation, 2011)
We thank Lazdam et al and Yuan et al for their interesting
comments on our study.1 Lazdam et al point out that in our study,
birth weight in offspring of mothers with preeclampsia was significantly lower than in controls, ...
Increasing respiratory dead space improves sleep disordered breathing and hypoxemia in patients with chronic mountain sickness
(The FASEB Journal, 2011-04-25)
Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia
(Circulation, 2010-07-19)
Background—Adverse events in utero may predispose to cardiovascular disease in adulthood. The underlying mechanisms are unknown. During preeclampsia, vasculotoxic factors are released into the maternal circulation by the ...
Exaggerated pulmonary hypertension during mild exercise in chronic mountain sickness
(CHEST, 2010-02)
Background: Chronic mountain sickness (CMS) is an important public health problem and is characterized by exaggerated hypoxemia, erythrocytosis, and pulmonary hypertension. While pulmonary hypertension is a leading cause ...
Systemic vascular dysfunction in patients with chronic mountain sickness
(CHEST, 2012-01-01)
Background: Chronic mountain sickness (CMS) is a major public health problem characterized by
exaggerated hypoxemia and erythrocytosis. In more advanced stages, patients with CMS often
present with functional and structural ...
Exercise induces rapid interstitial lung water accumulation in patients with chronic mountain sickness
(CHEST, 2012-04-04)
Background: Chronic mountain sickness (CMS) is a major public health problem in mountainous
regions of the world. In its more advanced stages, exercise intolerance is often found, but the
underlying mechanism is not ...
High altitude hypoxia and blood pressure dysregulation in adult chickens
(Journal of Developmental Origins of Health and Disease, 2013)
Although it is accepted that impaired placental perfusion in complicated pregnancy can slow fetal growth and programme an increased risk of cardiovascular dysfunction at adulthood, the relative contribution of reductions ...