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Apolipoprotein E/C1/C4/C2 gene cluster diversity in two native andean populations : Aymaras and Quechuas
(Annals of Human Genetics, 2012-07)
Summary.
The APOE/C1/C4/C2 gene cluster presents high relevance in lipid metabolism and, therefore, has important epidemiological implications. Here, we study for the first time the variation patterns of 25 polymorphisms ...
Genetic variations in the TP53 pathway in native americans strongly suggest adaptation to the high altitudes of the andes
(PLOS One, 2015-09-18)
Abstract.
The diversity of the five single nucleotide polymorphisms located in genes of the TP53 pathway (TP53, rs1042522; MDM2, rs2279744; MDM4, rs1563828; USP7, rs1529916; and
LIF, rs929271) were studied in a total of ...
High-altitude hypoxia and echocardiographic indices of pulmonary hypertension in male and female chickens at adulthood
(Circulation Journal, 2014-06)
Background: By combining the chick embryo model with incubation at high altitude (HA), the effects of chronic hypoxia on fetal growth, fetal cardiac and aortic wall remodeling and systemic arterial blood pressure at adulthood ...
Determinación de distancia recorrida y variación de parámetros respiratorios y cardiovasculares, antes y después de la prueba de caminata de 6 minutos, en nativos y residentes permanentes de altura clinicamente sanos
(Rev Med (La Paz), 2014-01)
Resumen.
Objetivo:Determinar la distancia recorrida y la variación de parámetros respiratorios
y cardiovasculares antes y después de la prueba de caminata de los 6 minutos
(PC6M) en nativos y residentes permanentes de ...
Ancient human genomes suggest three ancestral populations for present-day Europeans
(Nature, 2014-09-18)
We sequenced the genomes of a 7,000-year-old farmer from Germanyandeight 8,000-year-oldhunter-gatherersfromLuxembourg and Sweden. We analysed these and other ancient genomes1–4 with 2,345contemporaryhumanstoshowthatmostp ...
Repercusión funcional respiratoria de sobrepeso y obesidad en habitantes de gran altura
(COLEGIO MEDICO DE BOLIVIA, 2016-02)
RESUMEN.
A nivel mundial se ha visto un aumento del sobrepeso y obesidad y Bolivia no es la excepción, en la ciudad de La Paz existe 19,190 casos, en Cochabamba existe 12,231, y en Santa Cruz hay 7,731 casos, según datos ...
Hallazgos de función pulmonar en pacientes con EPOC a 3.600 m.s.n.m. en el Instituto Boliviano de Biología de Altura
(COLEGIO MEDICO DE BOLIVIA, 2016-02)
RESUMEN.
El instituto Boliviano de Biología de Altura (IBBA) a parte de la investigación realiza venta de servicios de pruebas de Función Pulmonar a diferentes centros de salud, considerado centro de referencia a nivel ...
Exaggerated exercise-induced pulmonary hypertension causes lung water accumulation and right ventricular dysfunction in patients with chronic mountain sickness
(High Altitude Medicine & Biology, 2010-08-08)
Adrenocortical suppression in highland chick embryos is restored during incubation at sea level
(High Altitude Medicine & Biology, 2011)
Abstract.
By combining the chick embryo model with incubation at high altitude, this study tested the hypothesis that
development at high altitude is related to a fetal origin of adrenocortical but not adrenomedullary ...
Response to letters regarding article, "Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia"
(Circulation, 2011)
We thank Lazdam et al and Yuan et al for their interesting
comments on our study.1 Lazdam et al point out that in our study,
birth weight in offspring of mothers with preeclampsia was significantly lower than in controls, ...