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Systemic vascular dysfunction in patients with chronic mountain sickness
(CHEST, 2012-01-01)
Background: Chronic mountain sickness (CMS) is a major public health problem characterized by
exaggerated hypoxemia and erythrocytosis. In more advanced stages, patients with CMS often
present with functional and structural ...
Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia
(Circulation, 2010-07-19)
Background—Adverse events in utero may predispose to cardiovascular disease in adulthood. The underlying mechanisms are unknown. During preeclampsia, vasculotoxic factors are released into the maternal circulation by the ...
High altitude hypoxia and blood pressure dysregulation in adult chickens
(Journal of Developmental Origins of Health and Disease, 2013)
Although it is accepted that impaired placental perfusion in complicated pregnancy can slow fetal growth and programme an increased risk of cardiovascular dysfunction at adulthood, the relative contribution of reductions ...
Genetic variations in the TP53 pathway in native americans strongly suggest adaptation to the high altitudes of the andes
(PLOS One, 2015-09-18)
Abstract.
The diversity of the five single nucleotide polymorphisms located in genes of the TP53 pathway (TP53, rs1042522; MDM2, rs2279744; MDM4, rs1563828; USP7, rs1529916; and
LIF, rs929271) were studied in a total of ...
Estudio comparativo de la función ventricular derecha en participantes sanos y mal crónico de montaña
(COLEGIO MEDICO DE BOLIVIA, 2016-02)
RESUMEN.
La HP es un evento que es visto en la altitud. El mal crónico de montaña es un síndrome de pérdida gradual de la capacidad de adaptación a la altura, con eritrocitosis excesiva, (Hb hombres > 21 gr/dl), severa ...
Repercusión funcional respiratoria de sobrepeso y obesidad en habitantes de gran altura
(COLEGIO MEDICO DE BOLIVIA, 2016-02)
RESUMEN.
A nivel mundial se ha visto un aumento del sobrepeso y obesidad y Bolivia no es la excepción, en la ciudad de La Paz existe 19,190 casos, en Cochabamba existe 12,231, y en Santa Cruz hay 7,731 casos, según datos ...
Hallazgos de función pulmonar en pacientes con EPOC a 3.600 m.s.n.m. en el Instituto Boliviano de Biología de Altura
(COLEGIO MEDICO DE BOLIVIA, 2016-02)
RESUMEN.
El instituto Boliviano de Biología de Altura (IBBA) a parte de la investigación realiza venta de servicios de pruebas de Función Pulmonar a diferentes centros de salud, considerado centro de referencia a nivel ...
RV contractility and exercise-induced pulmonary hypertension in chronic mountain sickness : a stress echocardiographic and tissue doppler imaging study
(ELSEVIER, 2013-12)
Objectives.
The aim of this study was to evaluate right ventricular (RV) and left ventricular function
and pulmonary circulation in chronic mountain sickness (CMS) patients with rest and stress echocardiography compared ...
Oxidative-nitrosative stress and systemic vascular function in highlanders with and without exaggerated hypoxemia
(CHEST, 2013-02-01)
Background: Acute exposure to high altitude stimulates free radical formation in lowlanders, yet
whether this persists during chronic exposure in healthy, well-adapted and maladapted highlanders suffering from chronic ...
Autosomal and X chromosome alu insertions in Bolivian aymaras and quechuas : two languages and one genetic pool
(American Journal of Human Biology, 2010)
Abstract.
Thirty-two polymorphic Alu insertions (18 autosomal and 14 from the X chromosome) were studied in
192 individuals from two Amerindian populations of the Bolivian Altiplano (Aymara and Quechua speakers: the two ...