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Higher estrogen levels during pregnancy in Andean than European residents of high altitude suggest differences in aromatase activity
(J Clin Endocrinol Metab, 2014-08)
Context: Uteroplacental hypoxia has been reported to lower estrogen levels in preeclampsia as the
result of reduced aromatase activity.
Objective: We asked whether the chronic hypoxia of residence at high altitude in the ...
Maternal and fetoplacental hypoxia do not alter circulating angiogenec growth effectors during human pregnancy
(Biol Reprod., 2014-02-27)
Abstract.
One causal model of preeclampsia (PE) postulates that
placental hypoxia alters the production of angiogenic growth
effectors (AGEs), causing an imbalance leading to maternal
endothelial cell dysfunction. We ...