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Neonatal oxygenation, pulmonary hypertension, and evolutionary adaptation to high altitutde (2013 Grover Conference series)
(Pulm Circ, 2015-03)
Abstract.
Andeans and Tibetans have less altitude reduction in birth weight than do shorter-resident
groups, but only Tibetans are protected from pulmonary hypertension and chronic mountain sickness
(CMS). We hypothesized ...
Maternal PRKAA1 and EDNRA genotypes are associated with birth weight, and PRKAA1 with uterine artery diameter and metabolic homeostasis at high altitude
(Physiol Genomics, 2014-07-14)
Low birth weight and intrauterine growth restriction (IUGR) increase the risk of mortality and
morbidity during the perinatal period as well as in adulthood. Environmental and genetic factors contribute to IUGR, but the ...
Greater uterine artery blood flow during pregnancy in multigenerational (Andean) than shorter-term (European) high-altitude residents
(Am J Physiol Regul Integr Comp Physiol, 2007)
Multigenerational (Andean) compared with shorter-term (European) high-altitude
residents exhibit less hypoxia-associated reductions in birth
weight. Because differences in arterial O2 content are not responsible,
we ...
Determinants of blood oxygenation during pregnancy in Andean and Europeas residents of high altitude
(Am J Physiol Regul Integr Comp Physiol, 2007-07-02)
High altitude decreases birth weight,
but this effect is diminished in long vs. short-resident, high-altitude
populations. We asked whether women from long vs. short-resident,
high-altitude populations had higher arterial ...
Pulmonary gas exchange in Andean nativos with excessive polycythemia - efecct of hemodilution
(J. Appl. Physiol., 1988)
Pulmonary gas exchange in andean natives (n =8) with excessive high-altitude (3,600-4,200 m) polycythemia (hematocrit 65.1 +- 6.6%) and hipoxemia (arterial PO2 45.6+-5.6 Torr) in the absence of pulmonary or cardiovascular ...