Comparaison de l'effet de l'exercice physique sur les fonctions plaquettaires et le facteur VIII chez les amérindiens vivant en haute altitude (3600 m) et chez les parisiens
Fecha
1976Autor
Drouet, L
Dosne, AM
Rodríguez-Zeballos, A
Ergueta, J
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Summary.
Highlanders natives studied at high altitude (La Paz, 3600 m) were compared with europeans studies at sea level (Paris), using physical exercise as a dynamic model for the investigation of hemostatic and coagulation functions.
It was concluded that the thrombocytosis found in men living in chronic hypoxia is not due to a particular redistribution of the platelet vascular pool:
- that the thrombocytosis and hyperaggregability following a sub maximal exercise depend on an adrenergic mechanism as at sea level.
- that the release of factor VIII from the vascular endothelial cell is independent from the liberation of plasminogen activators
- that the liberation of F VIII RA and his activation in F. VIII C could be depending in two different hormonal mechanisms which one possibly linked.