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Trypanosoma cruzi : a pharmacological comparison of some Bolivian isoenzymic strains
dc.contributor.author | Barnabe, C | |
dc.contributor.author | Tibayrenc, M | |
dc.contributor.author | Dujardin, JP | |
dc.date.accessioned | 2019-02-13T16:13:46Z | |
dc.date.available | 2019-02-13T16:13:46Z | |
dc.date.issued | 1983 | |
dc.identifier.uri | http://repositorio.umsa.bo/xmlui/handle/123456789/18813 | |
dc.description.abstract | Summary . The drug susceptibility of 3 isoenzymic strains of Trypanosoma cruzi was studied. Two drugs (SQ 18, 506 and Ro 7-1051) and 6 stocks were used. The drug test was carried out on epimastigote cultures. Significant susceptibility d¡fferences were found for Ro 7-1051 between the 3 strains. For SQ 18, 506, there were differences between strains 1 and 2, and 2 and 3, but no differences between 1 and 3. Strain 2 seemed more sensitive to SQ 18,506 than to Ro 7-1051. For strain 1, the opposite was observed. There was no difference of susceptibility for the two drugs in the case of strain 3. A great intrastrain variability was observed and the interstrain differences were not clearly proportional to the genetic distances Nevertheless, drug susceptibility was correlated in some degree to the biochemical classification. | es_ES |
dc.language.iso | en | es_ES |
dc.publisher | Ann. Soc. Belge Med. Trop. | es_ES |
dc.subject | TRYPANOSOMA CRUZI | es_ES |
dc.subject | ISOENZIMA | es_ES |
dc.subject | COMPARACIÓN FARMACOLÓGICA | es_ES |
dc.title | Trypanosoma cruzi : a pharmacological comparison of some Bolivian isoenzymic strains | es_ES |
dc.type | Article | es_ES |