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Les chimanines, nouvelles quinoleines substituées en 2, isolées d'une plante bolivienne antiparasitaire : galipéa longiflora
dc.contributor.author | Fournet, A | |
dc.contributor.author | Hocquemiller, R | |
dc.contributor.author | Roblot, F | |
dc.contributor.author | Cavé, A | |
dc.contributor.author | Richomme, P | |
dc.contributor.author | Bruneton, J | |
dc.date.accessioned | 2018-06-25T18:40:37Z | |
dc.date.available | 2018-06-25T18:40:37Z | |
dc.date.issued | 1993 | |
dc.identifier.uri | http://repositorio.umsa.bo/xmlui/handle/123456789/16744 | |
dc.description.abstract | ABSTRACT.-Petroleum ether and CHCI₃, extracts of stem, root bark, and leaves of Galipea longifora were found active in vitro against Leishmania sp. and Trypanosoma cruzi at 100 µg/ml. The activity-guided fractionation of the extracts by chromatography afforded thirteen active compounds identified as 2-substituted quinoline alkaloids. Four new 2-alkylquinoline alkaloids were isolated and identified from leaves or trunk bark of G. longiflora: 4-methoxy-2-n-propylquinoline [10] (chimanine A), 2-(E)-prop-1 ‘-enylquinoline [11] (chimanine B), 4- methoxy-2-(E)-prop-1’-enylquinoline [12) (chimanine C), and 2-( 1 ’,2 ’-trans-epoxypropyl)- quinoline [13] (chimanine D). These alkaloids are accompanied by eight known 2-substituted quinolines (2-9), and by one known furo-(2,3b)-quinoline alkaIoid, skimmianine [1]. | es_ES |
dc.language.iso | fr | es_ES |
dc.publisher | Journal of Natural Products | es_ES |
dc.subject | QUINOLÉINES NOUVELLES | es_ES |
dc.subject | GALIPEA LONGIFLORA | es_ES |
dc.title | Les chimanines, nouvelles quinoleines substituées en 2, isolées d'une plante bolivienne antiparasitaire : galipéa longiflora | es_ES |
dc.type | Article | es_ES |